FKBP1A anticorps (AA 43-74)

N° du produit ABIN392172

Cet anticorps anti-FKBP1A Polyclonal Lapin (Clone RB14521) (ABIN392172) détecte spécifiquement FKBP1A dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FKBP1A anticorps (AA 43-74) (ABIN392172)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14521

Détail du produit anti-FKBP1A anticorps

Épitope: AA 43-74

Homologie: B, M, Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This FKBP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-74 amino acids from the Central region of human FKBP12.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP12

Sujet: FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Poids moléculaire: 11951

ID gène: 2280

NCBI Accession: NP_000792, NP_463460

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process