Filamin A anticorps (AA 1025-1054)
Aperçu rapide pour Filamin A anticorps (AA 1025-1054) (ABIN392193)
Antigène
Voir toutes Filamin A (FLNA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1025-1054
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Homologie
- M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.
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Isotype
- Ig Fraction
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Indications d'application
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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Autre désignation
- FLNA
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Sujet
- Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
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Poids moléculaire
- 280739
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ID gène
- 2316
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NCBI Accession
- NP_001104026, NP_001447
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UniProt
- P21333
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Pathways
- TCR Signaling, Maintenance of Protein Location
Antigène
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