PTK7 anticorps (N-Term)

N° du produit ABIN392230

Cet anticorps Lapin Polyclonal détecte spécifiquement PTK7 dans WB, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour PTK7 anticorps (N-Term) (ABIN392230)

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB01501

Détail du produit anti-PTK7 anticorps

Épitope: AA 21-52, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCK4 (PTK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human CCK4 (PTK7).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PTK7 (ABIN392230)

Wang, Li, Yin, Wang, Wang, Wei, Guo, Ma, Shi, Zhou, Wang: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).

Détails sur PTK7

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Autre désignation: CCK4 (PTK7)

Sujet: CCK4 may function as a cell adhesion molecule. Although it belongs to the insuline receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.

Poids moléculaire: 118392

ID gène: 5754

NCBI Accession: NP_001257327, NP_002812, NP_690619, NP_690620, NP_690621

UniProt: Q13308

Pathways: Signalisation RTK, Tube Formation