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PIM2 anticorps (C-Term)

PIM2 Reactivité: Humain WB, IP, IHC (p) Hôte: Lapin Polyclonal RB01288 unconjugated
N° du produit ABIN392442
  • Antigène Voir toutes PIM2 Anticorps
    PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))
    Épitope
    • 10
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 277-308, C-Term
    Reactivité
    • 46
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 42
    • 6
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIM2 est non-conjugé
    Application
    • 34
    • 26
    • 22
    • 20
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.
    Clone
    RB01288
    Isotype
    Ig Fraction
  • Indications d'application
    IP: 1:50~100. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Pogacic, Bullock, Fedorov, Filippakopoulos, Gasser, Biondi, Meyer-Monard, Knapp, Schwaller: "Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity." dans: Cancer research, Vol. 67, Issue 14, pp. 6916-24, (2007) (PubMed).

  • Antigène
    PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))
    Autre désignation
    PIM2 (PIM2 Produits)
    Synonymes
    anticorps cb1068, anticorps fj47b05, anticorps pim2, anticorps wu:fj47b05, anticorps DXCch3, anticorps Pim-2, anticorps Pim-2 proto-oncogene, serine/threonine kinase, anticorps proviral integration site 2, anticorps pim2, anticorps PIM2, anticorps Pim2
    Sujet
    Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli, its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
    Poids moléculaire
    34190
    ID gène
    11040
    NCBI Accession
    NP_006866
    UniProt
    Q9P1W9
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