PPM1F anticorps (C-Term)

N° du produit ABIN392884

Détail du produit anti-PPM1F anticorps

Antigène: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Épitope: AA 409-439, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPM1F est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PPM1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human PPM1F.

Clone: RB5987

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PPM1F

Antigène: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Autre désignation: PPM1F (PPM1F Produits)

Synonymes: anticorps 1110021B16Rik, anticorps 4933427B07Rik, anticorps CaMKPase, anticorps Popx2, anticorps mKIAA0015, anticorps CAMKP, anticorps FEM-2, anticorps POPX2, anticorps hFEM-2, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1F, anticorps protein phosphatase 1F (PP2C domain containing), anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1F, anticorps PPM1F, anticorps Ppm1f

Sujet: PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.

Poids moléculaire: 49831

ID gène: 9647

NCBI Accession: NP_055449

UniProt: P49593

Pathways: Positive Regulation of Endopeptidase Activity