CD147 anticorps

N° du produit ABIN400674

Cet anticorps anti-CD147 est un anticorps Souris Monoclonal détectant CD147 dans FACS et IHC (p). Adapté pour Humain et Porc.

Aperçu rapide pour CD147 anticorps (ABIN400674)

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité: Humain, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-M6-2

Détail du produit anti-CD147 anticorps

Specificité: AM08322PU-N recognizes extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells, it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

Réactivité croisée (Details): Species reactivity (expected):Porcine.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: Basigin, BSG, EMMPRIN, TCSF, Leukocyte activation antigen M6, Collagenase stimulatoryfactor, Extracellular matrix metalloproteinase inducer, 5F7, Tumor cell-derived collagenasestimulatory factor, OK blood group antigen

Purification: Protein A Chromatography.

Immunogène: A soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for theentire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 andCH3 domain of human IgG1

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 15 mM Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: CD147

Sujet: CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3, probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

ID gène: 682

UniProt: P35613

Pathways: S100 Proteins