CDK2 anticorps

N° du produit ABIN400761

Cet anticorps anti-CDK2 est un anticorps Souris Monoclonal détectant CDK2 dans WB, IP, IHC (p) et EIA. Adapté pour Humain, Souris et Xenopus laevis.

Aperçu rapide pour CDK2 anticorps (ABIN400761)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain, Souris, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 4i33

Détail du produit anti-CDK2 anticorps

Specificité: Recognizes Human CDK2 (MW 33 kDa). Does not cross-react with other CDKs.

Réactivité croisée (Details): Species reactivity (expected):Xenopus and Mouse.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: p33 protein kinase, Cell division protein kinase 2, Cyclin dependent kinase 2

Purification: Protein G Chromatography

Immunogène: Recombinant Human CDK2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.85 mg/mL

Buffer: 0.1 M Tris-glycine, pH 7.4, 150 mM Sodium Chloride, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2

Sujet: Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

ID gène: 1017

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA