RAD23B anticorps (AA 163-176)

N° du produit ABIN401177

L’anticorps Chèvre Polyclonal anti-RAD23B a été validé pour WB et EIA. Il convient pour détecter RAD23B dans des échantillons de Humain, Chien, Chimpanzé et Saccharomyces cerevisiae.

Aperçu rapide pour RAD23B anticorps (AA 163-176) (ABIN401177)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain, Chien, Chimpanzé, Saccharomyces cerevisiae

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RAD23B anticorps

Épitope: AA 163-176

Specificité: Reactivity occurs against Human HR23B protein. Cross reactivity with HR23B protein from Mouse and Rat may also occur as sequence homology varies by one amino acid residue in this sequence by BLAST analysis. Reactivity with HR23B protein from other sources is not known.

Réactivité croisée (Details): Species reactivity (expected):Canine, Chimpanzee, S.cerevisiae.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase

Immunogène: Synthetic peptide corresponding aa 163-176 of human HR23B protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/2000 - 1/10000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: HR23B (also known as UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa protein and p58) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Synonyms: HR23B, UV excision repair protein RAD23 homolog B, XP-C repair-complementing complex 58 kDa protein

ID gène: 5887

NCBI Accession: NP_002865

UniProt: P54727

Pathways: Réparation de l'ADN