PNKP anticorps (Internal Region)
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- Antigène Voir toutes PNKP Anticorps
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Épitope
- Internal Region
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Reactivité
- Humain, Chimpanzé
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PNKP est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This affinity purified antibody is directed against PNK protein.
- Réactivité croisée (Details)
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Species reactivity (expected):Chimpanzee (100 %).Dog, mouse and rat (83 %).
Species reactivity (tested):Human. - Purification
- Immunoaffinity chromatography
- Immunogène
- Synthetic peptide corresponding to an internal region of human PNK protein
- Isotype
- IgG
- Top Product
- Discover our top product PNKP Anticorps primaire
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- Indications d'application
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ELISA: 1: 3,000 - 1: 12,000. Western blot: 1: 300 - 1: 1,500 (Expect a band approximately 57 kDa in size corresponding toPNK in the appropriate cell lysate or extract).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.46 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or for longer (in aliquots) at -20 °C or below.
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- Antigène
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
- Autre désignation
- PNKP (PNKP Produits)
- Synonymes
- anticorps EIEE10, anticorps MCSZ, anticorps PNK, anticorps Tb06.28P18.320, anticorps 21.m03011, anticorps 1810009G08Rik, anticorps polynucleotide kinase 3'-phosphatase, anticorps hypothetical protein, anticorps polynucleotide kinase 3'- phosphatase, anticorps PNKP, anticorps Pnkp, anticorps Tc00.1047053507017.50, anticorps Tc00.1047053505807.190, anticorps Tb927.6.1580, anticorps BBOV_IV000690, anticorps CC1G_05202, anticorps PGTG_20262, anticorps PGTG_18987, anticorps pnkp.S, anticorps pnkp
- Sujet
- Mammalian PNK (also known as PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'- hosphatase and Polynucleotide kinase) catalyzes the 5' phosphorylation of nucleic acids and can have associated 3' phosphatase activity, predictive of an important function in DNA repair following ionizing radiation or oxidative damage. PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine.Synonyms: Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase
- ID gène
- 11284
- NCBI Accession
- NP_009185
- UniProt
- Q96T60
- Pathways
- Réparation de l'ADN, Nucleotide Phosphorylation
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