LIM Domain Kinase 1 anticorps (AA 630-647)

N° du produit ABIN401293

Cet anticorps Lapin Polyclonal détecte spécifiquement LIM Domain Kinase 1 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chimpanzé et Orang-Utan.

Aperçu rapide pour LIM Domain Kinase 1 anticorps (AA 630-647) (ABIN401293)

Antigène: LIM Domain Kinase 1 (LIMK1)

Reactivité: Humain, Souris, Rat, Chimpanzé, Orang-Utan

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Kinase 1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-LIM Domain Kinase 1 anticorps

Épitope: AA 630-647

Specificité: This antibody reacts to LIM kinase protein.

Réactivité croisée (Details): Species reactivity (expected):Chimpanzee, Orangutan, Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogène: Synthetic peptide corresponding aa 630-647 of human LIM kinase protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/8000 - 1/36000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur LIM Domain Kinase 1

Antigène: LIM Domain Kinase 1 (LIMK1)

Autre désignation: LIMK1

Sujet: LIM Kinase is also known as LIM-domain containing protein kinase, LIMK-1 and LIMK. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified. LIM kinase has a cytoplamic localization.Synonyms: EC=2.7.11.1, LIM domain kinase 1, LIMK, LIMK-1

ID gène: 3984

NCBI Accession: NP_001191355

UniProt: P53667

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events