CAMK2A anticorps (AA 6-23)
Aperçu rapide pour CAMK2A anticorps (AA 6-23) (ABIN401305)
Antigène
Voir toutes CAMK2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 6-23
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Specificité
- This antibody is directed against human CaM Kinase II protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Orangutan, Zebrafish, Chicken, Porcine, Rabbit, Frog.
Species reactivity (tested):Human. -
Purification
- Affinity Purified
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Immunogène
- Synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein
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Isotype
- IgG
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Indications d'application
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ELISA: 1/4,000 - 1/20,000. Western Blot: 1/1,000 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.57 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azi
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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Autre désignation
- CAMK2A
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Sujet
- CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968
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ID gène
- 815
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NCBI Accession
- NP_741960
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UniProt
- Q9UQM7
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Pathways
- Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
Antigène
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