MARCKS anticorps (pSer162)

N° du produit ABIN401578

Cet anticorps Lapin Polyclonal détecte spécifiquement MARCKS dans IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MARCKS anticorps (pSer162) (ABIN401578)

Antigène: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCKS est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-MARCKS anticorps

Épitope: pSer162

Specificité: Antibody AP09479PU detects endogenous levels of MARCKS only when phosphorylated at Serine 162.

Purification: Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: The antiserum was produced against synthesized phosphopeptide derived from human MARCKS around the phosphorylation site of serine 162 (K-K-Sp-F-K).

Information d'application

Indications d'application: Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur MARCKS

Antigène: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Autre désignation: MARCKS

Sujet: MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL

ID gène: 4082

NCBI Accession: NP_002347

UniProt: P29966