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Tyrosine Hydroxylase anticorps (pSer19)

Cet anticorps Lapin Polyclonal détecte spécifiquement Tyrosine Hydroxylase dans IF. Il présente une réactivité envers Rat.
N° du produit ABIN401584

Aperçu rapide pour Tyrosine Hydroxylase anticorps (pSer19) (ABIN401584)

Antigène

Voir toutes Tyrosine Hydroxylase (TH) Anticorps
Tyrosine Hydroxylase (TH)

Reactivité

  • 137
  • 133
  • 116
  • 11
  • 9
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Rat

Hôte

  • 139
  • 26
  • 7
  • 5
  • 2
Lapin

Clonalité

  • 125
  • 54
Polyclonal

Conjugué

  • 110
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application

  • 133
  • 90
  • 58
  • 46
  • 30
  • 24
  • 22
  • 21
  • 15
  • 14
  • 13
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Épitope

    • 20
    • 15
    • 14
    • 14
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer19

    Specificité

    Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19.

    Purification

    Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogène

    The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q).
  • Indications d'application

    Immunofluorescence: 1/100approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store the antibody (in aliquots) at-20 °C.
  • Antigène

    Tyrosine Hydroxylase (TH)

    Autre désignation

    Tyrosine 3-Monooxygenase (TH)

    Sujet

    Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's diseaseSynonyms: TYH, Tyrosine 3-hydroxylase

    ID gène

    7054

    NCBI Accession

    NP_000351

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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