Metabotropic Glutamate Receptor 6 anticorps (C-Term)

N° du produit ABIN437971

Cet anticorps Lapin Polyclonal détecte spécifiquement Metabotropic Glutamate Receptor 6 dans WB, IHC et ICC. Il présente une réactivité envers Rat et Souris.

Aperçu rapide pour Metabotropic Glutamate Receptor 6 anticorps (C-Term) (ABIN437971)

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-Metabotropic Glutamate Receptor 6 anticorps

Épitope: C-Term

Purification: affinity purified

Immunogène: AAPPQNENAEDAK
Corresponding to the carboxyterminus of rat mGluR6

Isotype: IgG

Information d'application

Indications d'application: Suggested dilutions:
Western blot: 1:2000-1:3000
Immunohistochemistry: 1:300
Dilutions listed as a recommendation. Optimal dilution should be determined by investigator

Commentaires:

This antibody is useful for Western blot, where a band is seen at approx. 96 kDa. Neurons of expected brain regions stain well. Staining is not recommended for human or rat tissues
Note: A customer found a band in the 60-70 kDa range corresponding to the mGluR6 precursor.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1 % BSA, Tris-glycine with 0.1 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Aliquot as undiluted antisera and immediately place at -20°C.
Antisera may have become trapped in top of vial during shipping. Centrifugation of vial is recommended before opening.
Repeated freeze/thaw cycles compromise the integrity of the antiserum.

Stock: -20 °C

Date de péremption: 6 months

Détails sur Metabotropic Glutamate Receptor 6

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Autre désignation: mGluR6

Sujet: Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.