Unc5c anticorps (Internal Region)
Aperçu rapide pour Unc5c anticorps (Internal Region) (ABIN452309)
Antigène
Voir toutes Unc5c AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- NCTVSEEPTG ID
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Specificité
- This antibody recognizes UNC5C.
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Réactivité croisée (Details)
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Species reactivity (expected):Human, Canine.
Species reactivity (tested):Mouse. -
Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogène
- Peptide with sequence NCTVSEEPTGID, from the internal region of the protein sequence . Genename: UNC5C
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Indications d'application
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Peptide ELISA: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))
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Autre désignation
- UNC5C
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Sujet
- UNC5C is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It is also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. There are two named isoforms.Synonyms: Netrin receptor UNC5C, Protein unc-5 homolog C, UNC5H3, Unc-5 homolog 3
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ID gène
- 8633
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NCBI Accession
- NP_003719
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UniProt
- O95185
Antigène
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