Unc5c anticorps (Internal Region)

N° du produit ABIN452309

Détail du produit anti-Unc5c anticorps

Antigène: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Épitope: Internal Region

Reactivité: Humain, Souris, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Unc5c est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Séquence: NCTVSEEPTG ID

Specificité: This antibody recognizes UNC5C.

Réactivité croisée (Details): Species reactivity (expected):Human, Canine.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence NCTVSEEPTGID, from the internal region of the protein sequence . Genename: UNC5C

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Unc5c

Antigène: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Autre désignation: UNC5C (Unc5c Produits)

Synonymes: anticorps UNC5C, anticorps UNC5H3, anticorps 6030473H24, anticorps AI047720, anticorps B130051O18Rik, anticorps Unc5h3, anticorps rcm, anticorps wu:fb03d07, anticorps unc-5 netrin receptor C, anticorps UNC5C, anticorps Unc5c, anticorps unc5c

Sujet: UNC5C is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It is also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. There are two named isoforms.Synonyms: Netrin receptor UNC5C, Protein unc-5 homolog C, UNC5H3, Unc-5 homolog 3

ID gène: 8633

NCBI Accession: NP_003719

UniProt: O95185