IL-2 anticorps

N° du produit ABIN452489

L’anticorps anti-IL-2 Monoclonal Souris est utilisé pour la détection de IL-2 dans des échantillons de Humain. Il a été validé pour EIA et ELISA (Detection).

Aperçu rapide pour IL-2 anticorps (ABIN452489)

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-2 est non-conjugé

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: 5A8

Détail du produit anti-IL-2 anticorps

Specificité: Recognizes Interleukin-2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: IL-2, TCGF, T-cell growth factor

Purification: Affinity Chromatography on Protein G.

Immunogène: Recombinant Human Interleukin-2 (IL2)

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: Clone 5A8 can be used as Detection antibody to detect recombinant Human IL-2 inELISA when clone 9F9 is used as Capture antibody. Clone 5A8 can be reversely used as Capture antibody as well. However it produced betterresults when used as Detection antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.00 mg/mL

Concentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-2

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Autre désignation: Interleukin-2 / IL2

Sujet: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

ID gène: 3558

UniProt: P60568

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation