IL-2 anticorps

N° du produit ABIN452494

Cet anticorps Souris Monoclonal détecte spécifiquement IL-2 dans EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL-2 anticorps (ABIN452494)

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-2 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: 6B1

Détail du produit anti-IL-2 anticorps

Specificité: Recognizes Interleukin-2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: IL-2, TCGF, T-cell growth factor

Purification: Affinity Chromatography on Protein G.

Immunogène: Recombinant Human Interleukin-2 (IL2)

Isotype: IgG1

Information d'application

Indications d'application: ELISA: Clone 6B1 can match with clone 9F9 in Sandwich ELISA to detect the recombinanthuman IL-2 antigen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/mL

Concentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-2

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Autre désignation: Interleukin-2 / IL2

Sujet: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

ID gène: 3558

UniProt: P60568

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation