Prostate Specific Antigen anticorps (free)
Aperçu rapide pour Prostate Specific Antigen anticorps (free) (ABIN452574)
Antigène
Voir toutes Prostate Specific Antigen (PSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- free
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Specificité
- Reacts with both complexed and free Human PSA.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Attributs du produit
- Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Purified Human PSA.
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Isotype
- IgG2a
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Indications d'application
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ELISA: This monoclonal PSA antibody can be used as a Tracer/Detection antibody in aSandwich ELISA for Human free PSA detection in combination with a free PSA specificCapture antibody (Cat##ABIN452575).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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Buffer
- 0.01 M PBS, pH 7.0 without preservatives
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody at -20 °C. After reconstitution, aliquot and store at -20 °C.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Prostate Specific Antigen (PSA)
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Autre désignation
- Kallikrein-3 / PSA / KLK3
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Sujet
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase
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ID gène
- 354
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UniProt
- P07288
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Pathways
- Système du Complément
Antigène
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