Coagulation Factor IX anticorps
Aperçu rapide pour Coagulation Factor IX anticorps (ABIN452591)
Antigène
Voir toutes Coagulation Factor IX (F9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Human Factor IX.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Attributs du produit
- Synonyms: Christmas factor, PTC, Plasma thromboplastin component
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Human Factor IX.
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Isotype
- IgG1
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Indications d'application
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with Double distillated water to a final concentration of 1.0 mg/mL.
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Buffer
- 0.01 M PBS, pH 7.2 without preservatives.
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Coagulation Factor IX (F9)
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Sujet
- Factor IX circulates in the blood as an inactive zymogen at the normal concentration of approximately 3 μg/mL. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca2+ ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X linked disorder, also called hemophilia B or Christmas disease. The disease affects approximately 1 in 50,000 of the population (almost exclusively males).Synonyms: Christmas factor, PTC, Plasma thromboplastin component
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ID gène
- 2158
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UniProt
- P00740
Antigène
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