ALS2 anticorps (C-Term)

N° du produit ABIN452733

Cet anticorps anti-ALS2 est un anticorps Lapin Polyclonal détectant ALS2 dans WB et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour ALS2 anticorps (C-Term) (ABIN452733)

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALS2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ALS2 anticorps

Épitope: C-Term

Specificité: This antibody detects Alsin / ALS2 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2

Information d'application

Indications d'application: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur ALS2

Antigène: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Autre désignation: Alsin / ALS2

Sujet: ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.Synonyms: ALS2CR6, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis protein 2, KIAA1563

Poids moléculaire: 183666 Da

ID gène: 57679

NCBI Accession: NP_001129217

UniProt: Q96Q42

Pathways: Skeletal Muscle Fiber Development