Cathepsin F anticorps (Middle Region)

N° du produit ABIN452888

Détail du produit anti-Cathepsin F anticorps

Antigène: Cathepsin F (CTSF)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin F est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Cathepsin F at Center, D276.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide selected from the Center region of human CTSF

Information d'application

Indications d'application: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Cathepsin F

Antigène: Cathepsin F (CTSF)

Autre désignation: Cathepsin F (CTSF Produits)

Synonymes: anticorps CTSF, anticorps MGC140519, anticorps cb420, anticorps sb:cb420, anticorps zgc:153093, anticorps LOC100101596, anticorps Ctsf, anticorps ACYPI000376, anticorps catf, anticorps CATSF, anticorps CLN13, anticorps AI481912, anticorps cathepsin F, anticorps cathepsin W, anticorps CTSF, anticorps ctsf, anticorps Ctsf, anticorps ctsw, anticorps Tsp_02382

Sujet: Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway.Synonyms: CATSF, CTSF

Poids moléculaire: 53366 Da

ID gène: 8722

NCBI Accession: NP_003784

UniProt: Q9UBX1