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MME anticorps (C-Term)

Name: MME anticorps (C-Term)
SKU: ABIN453219
Price: 899.85 EUR
Availability: InStock

MME Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated

Western blot analysis of Neprilysin Antibody (C-term) in A2058,A375,Ramos cell line lysates (35ug/lane). (MME anticorps (C-Term))

Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MME anticorps (C-Term))

IHC (p)

2 images

N° du produit ABIN453219

Fiche de données

Antigène Voir toutes MME Anticorps

MME (Membrane Metallo-Endopeptidase (MME))
Épitope
16

13

9

8

8

7

7

7

6

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reactivité
207

57

50

3

2

2

2

2

2

1

1

1

1
Humain
Hôte
108

104

2
Lapin
Anticorps secondaires appropriés
Clonalité
109

104

2
Polyclonal
Conjugué
104

19

18

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MME est non-conjugé
Application
131

96

80

69

38

28

21

19

13

13

10

8

5

5

5

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité

This antibody reacts to Neprilysin (CD10).

Purification

Affinity chromatography on Protein A

Immunogène

KLH conjugated synthetic peptide selected from the C-terminal region of human Neprilysin

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anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivité: Humain WB, IHC, StM Hôte: Souris Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
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anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME Reactivité: Humain FACS, WB, IHC, ELISA, ICC, Neut Hôte: Souris Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivité: Humain WB, IHC, ELISA, StM, Coat Hôte: Souris Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.25 mg/mL

Buffer

PBS with 0.09 % (W/V) sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freezing and thawing.

Stock

4 °C/-20 °C

Stockage commentaire

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène

MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation

CD10 / Neprilysin (MME Produits)

Synonymes

anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme

Classe de substances

Chemical

Sujet

MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11

ID gène

4311

NCBI Accession

NP_000893

UniProt

P08473

Pathways

Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration