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PABP anticorps (Middle Region)

PABPC1 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN453247
  • Antigène Voir toutes PABP (PABPC1) Anticorps
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Épitope
    • 15
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 21
    • 21
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 33
    • 3
    Lapin
    Clonalité
    • 33
    • 3
    Polyclonal
    Conjugué
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PABP est non-conjugé
    Application
    • 29
    • 14
    • 14
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to PABPC1.
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation
    Immunogène
    KLH conjugated synthetic peptide selected from the Center region of human PABPC1
    Top Product
    Discover our top product PABPC1 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Autre désignation
    PABPC1 (PABPC1 Produits)
    Synonymes
    anticorps PAB1, anticorps PABP, anticorps PABP1, anticorps PABPC2, anticorps PABPL1, anticorps Pabp1, anticorps PabpI, anticorps Pabpl1, anticorps ePAB, anticorps Pabp, anticorps pab1, anticorps pabp, anticorps pabp1, anticorps pabpc1, anticorps pabpc2, anticorps PABPC1, anticorps wu:fb16a02, anticorps wu:fi19b08, anticorps wu:fj12d09, anticorps wu:fj61f06, anticorps zgc:109879, anticorps zgc:77608, anticorps poly(A) binding protein cytoplasmic 1, anticorps poly(A) binding protein, cytoplasmic 1, anticorps poly(A) binding protein, cytoplasmic 1 S homeolog, anticorps poly(A) binding protein cytoplasmic 1 like, anticorps poly(A) binding protein, cytoplasmic 1 L homeolog, anticorps poly(A) binding protein, cytoplasmic 1a, anticorps poly A binding protein, cytoplasmic 1 b, anticorps PABPC1, anticorps Pabpc1, anticorps pabpc1.S, anticorps pabpc1, anticorps PABPC1L, anticorps pabpc1.L, anticorps pabpc1a, anticorps pabpc1b
    Sujet
    PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.Synonyms: PAB1, PABP-1, PABP1, PABPC2, Poly(A)-binding protein 1, Polyadenylate-binding protein 1
    ID gène
    26986
    NCBI Accession
    NP_002559
    UniProt
    P11940
    Pathways
    SARS-CoV-2 Protein Interactome
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