PDIA3 anticorps (Middle Region)
Aperçu rapide pour PDIA3 anticorps (Middle Region) (ABIN453257)
Antigène
Voir toutes PDIA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody reacts to PDIA3.
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide selected from the Center region of human PDIA3
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Autre désignation
- PDIA3
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Sujet
- PDIA3 is the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.Synonyms: Disulfide isomerase ER-60, ER marker, ERP57, ERP60, GRP58, Protein Disulfide Isomerase, Protein disulfide-isomerase A3
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ID gène
- 2923
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NCBI Accession
- NP_005304
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UniProt
- P30101
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Antigène
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