IL12A anticorps (C-Term)

N° du produit ABIN453700

Détail du produit anti-IL12A anticorps

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to IL12A.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human IL12A

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL12A

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Autre désignation: Interleukin-12 alpha / IL12A (IL12A Produits)

Synonymes: anticorps CLMF, anticorps IL-12A, anticorps NFSK, anticorps NKSF1, anticorps P35, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12p35, anticorps Il-12a, anticorps Ll12a, anticorps p35, anticorps IL12p35, anticorps Il-12 p35, anticorps IL12p40, anticorps IL12, anticorps IL-12 p35, anticorps interleukin 12A, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12a, anticorps Interleukin 12 level, anticorps IL12A, anticorps IL12B, anticorps Il12b, anticorps Il12a, anticorps IL12, anticorps il12a

Sujet: IL12A is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1

ID gène: 3592

NCBI Accession: NP_000873

UniProt: P29459

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation