NLRP12 anticorps (C-Term)

N° du produit ABIN453767

Détail du produit anti-NLRP12 anticorps

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to NALP2.

Purification: Affinity chrmatography on Protein A

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human NLRP12

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NALP12 (NLRP12 Produits)

Synonymes: anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.Synonyms: LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NLRP12, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO, Regulated by nitric oxide

ID gène: 91662

NCBI Accession: NP_150639

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome