Retinoblastoma 1 anticorps (C-Term)
Aperçu rapide pour Retinoblastoma 1 anticorps (C-Term) (ABIN453807)
Antigène
Voir toutes Retinoblastoma 1 (RB1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody reacts to RB1.
-
Purification
- Saturated Ammonium Sulfate (SAS) precipitation
-
Immunogène
- KLH conjugated synthetic peptide selected from the C-terminal region of human RB1
-
-
-
-
Indications d'application
-
ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium az
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Retinoblastoma 1 (RB1)
-
Autre désignation
- Retinoblastoma-Associated Protein / RB1
-
Sujet
- RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
-
ID gène
- 5925
-
NCBI Accession
- NP_000312
-
UniProt
- P06400
-
Pathways
- Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
Antigène
-