GM-CSF anticorps (HRP)
Aperçu rapide pour GM-CSF anticorps (HRP) (ABIN453899)
Antigène
Voir toutes GM-CSF (CSF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This monoclonal antibody reacts with natural and recombinant human GM-CSF. Does not show any cross reaction with other human Cytokines or Growth Factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL1-beta, TGFbeta-1 and TNF-alpha.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Immunogène
- Purified recombinant Human GM-CSF.
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Isotype
- IgG1
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Indications d'application
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ELISA: This HRP-conjugated monoclonal antibody can be used as a Tracer/Detectionantibody in Sandwich ELISA applications for human GM-CSF detection in combination witha Capture antibody (Cat#DM1014). Suggested Capture Coating Dose: approx. 0.3 μg/mL. Substrate: TMB. If the above suggested conditions are followed approximately 2 pg/mL ofGM-CSF in serum/ plasma or medium can be detected with an assay range of 0-500 pg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % Thimerosal as a bacteriostat.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Autre désignation
- GM-CSF
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Sujet
- The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim
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ID gène
- 1437
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NCBI Accession
- NP_000749
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UniProt
- P04141
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Pathways
- Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin
Antigène
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