VCAM1 anticorps (Biotin)
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- Antigène Voir toutes VCAM1 Anticorps
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VCAM1 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- The mouse monoclonal antibody STA recognizes an extracellular epitope of CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
- Réactivité croisée (Details)
- Human
- Purification
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Immunogène
- Human DS6 T cell line
- Clone
- STA
- Isotype
- IgG1
- Top Product
- Discover our top product VCAM1 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 5-6 μg/mL, positive control: TNF-alpha activated HUVEC cells.
- Commentaires
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The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Do not freeze.
Avoid prolonged exposure to light. - Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." dans: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).
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Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro." dans: Journal of virology, Vol. 80, Issue 6, pp. 2684-93, (2006) (PubMed).
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- Antigène
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- Autre désignation
- CD106 (VCAM1 Produits)
- Synonymes
- anticorps CD106, anticorps INCAM-100, anticorps Vcam-1, anticorps VCAM1B, anticorps fi76d06, anticorps wu:fi76d06, anticorps zgc:158875, anticorps VCAM1, anticorps vascular cell adhesion molecule 1, anticorps vascular cell adhesion molecule 1b, anticorps VCAM1, anticorps Vcam1, anticorps vcam1b, anticorps VCAM-1
- Sujet
- Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.,VCAM-1, INCAM-100
- ID gène
- 7412
- UniProt
- P19320
- Pathways
- Carbohydrate Homeostasis
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