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- Antigène Voir toutes CD22 Anticorps
- CD22 (CD22 Molecule (CD22))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD22 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- The antibody IS7 reacts with an extracellular epitope of CD22 (BL-CAM), a 130 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed in the cytoplasm of pro-B and pre-B lymphocytes, and on the surface of mature and activated B lymphocytes, it is lost on plasma cells, peripheral blood T lymphocytes, granulocytes and monocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- human cell line Reh
- Clone
- IS7
- Isotype
- IgG1
- Top Product
- Discover our top product CD22 Anticorps primaire
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reactivité: Humain FACS, WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 2H1C4 unconjugated
anti-CD22 Molecule (CD22) (AA 621-725) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, ICC Hôte: Souris Monoclonal 1A3A11 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, IHC, IF, Coat, StM Hôte: Souris Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, IHC, IF, Coat Hôte: Souris Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivité: Humain, Non-Human Primate FACS, WB, IP Hôte: Souris Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reactivité: Humain FACS Hôte: Souris Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivité: Humain, Souris, Rat, Singe, Chien WB, IHC, IHC (p) Hôte: Souris Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain IHC Hôte: Lapin Monoclonal MSVA-022R unconjugated Recombinant Antibody
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL, Positive control: lysed whole blood, lyse-wash protocol
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- CD22 (CD22 Molecule (CD22))
- Autre désignation
- CD22 (CD22 Produits)
- Synonymes
- anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
- Sujet
- CD22 Molecule,CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.,SIGLEC2, SIGLEC-2
- ID gène
- 933
- UniProt
- P20273
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