TTR anticorps

N° du produit ABIN458186

Détail du produit anti-TTR anticorps

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Porc

Clonalité: Polyclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Immunoelectrophoresis (IEP)

Specificité: Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.

Attributs du produit: Precipitating polyclonal swine antiserum to human transthyretin (prealbumin)

Purification: Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

Immunogène: Transthyretin is the fastest protein in the immunoelectrophoresis pattern of human serum. It consists of four identical polypeptide chins with no carbohydrate. The molecular weight is 55,000 and the concentration in normal serum ranges from 100 to 400 µ g/ml. It can bind thyroxine and retinal and its concentration is reduced in severe liver diseases. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotype: IgG

Information d'application

Indications d'application: In precipitating techniques as immunoelectrophoresis and single and double radial immuno-diffusion (Mancini, Ouchterlony) to identify the presence of transthyretin or to determine its concentration. The presence of non-precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in non-precipitating antibody-binding techniques if proper controls are included.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled swine serum. No foreign proteins added. Antibody titre: Precipitin titre not less than 1:64 when tested against normal human plasma in agar-block immunodiffusio

Buffer: Delipidated, heat inactivated, lyophilized, stable whole serum.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: Transthyretin (Prealbumin) (TTR Produits)

Synonymes: anticorps zgc:103583, anticorps TTR, anticorps LOC100226992, anticorps CTS, anticorps CTS1, anticorps HsT2651, anticorps PALB, anticorps TBPA, anticorps AA408768, anticorps AI787086, anticorps D17860, anticorps prealbumin, anticorps Lr1, anticorps Tbpa, anticorps Prealbumin, anticorps xTTR, anticorps transthyretin (prealbumin, amyloidosis type I), anticorps transthyretin, anticorps Transthyretin, anticorps transthyretin (prealbumin, amyloidosis type 1), anticorps transthyretin-like, anticorps transthyretin L homeolog, anticorps ttr, anticorps TTR, anticorps vpb38, anticorps MRAD2831_RS38185, anticorps Caci_4246, anticorps LOC100226992, anticorps Ttr, anticorps ttr.L

Sujet: Tested in immunoelectrophoresis and double radial immunodiffusion against normal human serum the precipitin line obtained shows a reaction of full identity with the purified immunogen. The product does not react with any other proteins component of human serum or plasma

Pathways: Hormone Transport