Sphingomyelin Synthase 2 anticorps

N° du produit ABIN4620351

Détail du produit anti-Sphingomyelin Synthase 2 anticorps

Antigène: Sphingomyelin Synthase 2 (SGMS2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sphingomyelin Synthase 2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Sphingomyelin Synthase 2.

Purification: Antigen Immunoaffinity Chromatography

Immunogène: Synthetic peptide derived from the Human Sphingomyelin Synthase 2 protein

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/400 as starting dilution. Immunohistochemistry: 1/400 as starting dilution. Positive control: Brain, heart, kidney, liver, muscle and stomach.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Sphingomyelin Synthase 2

Antigène: Sphingomyelin Synthase 2 (SGMS2)

Autre désignation: SGMS2 (SGMS2 Produits)

Synonymes: anticorps SMS2, anticorps 4933405A16Rik, anticorps 5133401H06Rik, anticorps AI854299, anticorps RGD1305778, anticorps spermatin, anticorps sphingomyelin synthase 2, anticorps sgms2, anticorps SGMS2, anticorps Sgms2

Sujet: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SMS2, Sphingomyelin synthase 2

ID gène: 166929

NCBI Accession: NP_001129729

UniProt: Q8NHU3