FBXW7 anticorps
Aperçu rapide pour FBXW7 anticorps (ABIN4620357)
Antigène
Voir toutes FBXW7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects FBXW7, widely expressed.
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Purification
- Affinty chromatograpghy
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Immunogène
- Synthetic peptide dervied from the human FBXW7 protein
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 Reactivité: Humain, Souris, Rat WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Drosophila melanogaster, Singe, Xenopus laevis, Hamster, Roussette (Chauve-souris), Poulet WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 Reactivité: Souris, Rat, Hamster WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 Reactivité: Humain WB, IHC, ELISA, IHC (p) Hôte: Souris Monoclonal 3D1 unconjugated
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Indications d'application
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Autre désignation
- FBXW7
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Sujet
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
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ID gène
- 55294
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NCBI Accession
- NP_001013433
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UniProt
- Q969H0
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Pathways
- Signalisation Notch, EGFR Signaling Pathway
Antigène
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