GLI1 anticorps

N° du produit ABIN4620372

L’anticorps anti-GLI1 Polyclonal Lapin est utilisé pour la détection de GLI1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour GLI1 anticorps (ABIN4620372)

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLI1 anticorps

Specificité: This antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.

Purification: Affinity chromatography

Immunogène: Synthetic peptide derived from human zinc finger protein GLI1

Information d'application

Indications d'application: Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: GLI1

Sujet: Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.Synonyms: GLI, GLI-1, Glioma-associated oncogene, Oncogene GLI, Zinc finger protein GLI1

ID gène: 2735

NCBI Accession: NP_001153517

UniProt: P08151

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis