PRDM1 anticorps (C-Term)

N° du produit ABIN487993

Détail du produit anti-PRDM1 anticorps

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is expected to recognize both reported isoforms (NP_001189.2 and NP_878911.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-KVKQETVEPMDP, from the C Terminus of the protein sequence according to NP_001189.2, NP_878911.1.

Information d'application

Indications d'application: Peptide ELISA: 1/2000. Western blot: Approx 100 kDa band observed in Human Brain (cerebellum) lysates(calculated MW of 91.0 kDa according to NP_001189.2 and of 76.8 according toNP_878911.1). Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: PRDM1 / BLIMP1 (PRDM1 Produits)

Synonymes: anticorps GB11750, anticorps CG5249, anticorps Dmel\\CG5249, anticorps blimp-1, anticorps dBlimp-1, anticorps dBlimp1, anticorps Blimp-1, anticorps Blimp1, anticorps nrd, anticorps prdm1, anticorps ubo, anticorps wu:fb99c12, anticorps zgc:91885, anticorps MGC52536, anticorps PRDM1, anticorps blimp1, anticorps xblimp1, anticorps prdi-bf1, anticorps BLIMP1, anticorps PRDI-BF1, anticorps ZNFPR1A1, anticorps PR/SET domain 1, anticorps probable serine/threonine-protein kinase DDB_G0282963, anticorps CG5249 gene product from transcript CG5249-RF, anticorps blimp-1, anticorps PR domain containing 1a, with ZNF domain, anticorps PR domain 1 S homeolog, anticorps B lymphocyte induced maturation protein 1, anticorps PR domain 1, anticorps PR domain containing 1, with ZNF domain, anticorps PRDM1, anticorps LOC408295, anticorps Blimp-1, anticorps CpipJ_CPIJ007425, anticorps prdm1a, anticorps prdm1.S, anticorps prdm1, anticorps Prdm1

Sujet: PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction.Synonyms: BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI-BF1, PRDI-binding factor 1, Positive regulatory domain I-binding factor 1

ID gène: 639

NCBI Accession: NP_001189

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation