PRDM1 anticorps (C-Term)

N° du produit ABIN487993

Cet anticorps Chèvre Polyclonal détecte spécifiquement PRDM1 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Porc et Boeuf (Vache).

Aperçu rapide pour PRDM1 anticorps (C-Term) (ABIN487993)

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PRDM1 anticorps

Épitope: C-Term

Specificité: This antibody is expected to recognize both reported isoforms (NP_001189.2 and NP_878911.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-KVKQETVEPMDP, from the C Terminus of the protein sequence according to NP_001189.2, NP_878911.1.

Information d'application

Indications d'application: Peptide ELISA: 1/2000. Western blot: Approx 100 kDa band observed in Human Brain (cerebellum) lysates(calculated MW of 91.0 kDa according to NP_001189.2 and of 76.8 according toNP_878911.1). Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: PRDM1 / BLIMP1

Sujet: PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction.Synonyms: BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI-BF1, PRDI-binding factor 1, Positive regulatory domain I-binding factor 1

ID gène: 639

NCBI Accession: NP_001189

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation