Retinoblastoma 1 anticorps (HRP)

N° du produit ABIN4880121

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoblastoma 1 dans . Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Retinoblastoma 1 anticorps (HRP) (ABIN4880121)

Antigène: Retinoblastoma 1 (RB1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma 1 est conjugé à/à la HRP

Application: Veuillez nous consulter SVP

Clone: 1F8

Détail du produit anti-Retinoblastoma 1 anticorps (HRP)

Specificité: This antibody recognises retinoblastoma-associated protein (RB), a 105 kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.

Purification: Purified on protein A from tissue culture supernatant.

Immunogène: Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 of human Rb gel purified from bacterial lysates

Isotype: IgG1

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration

Commentaires:

Myeloma, fusion partnersCells from immunized Balb/c mice were fused with the Sp2/0-Ag.14 myeloma cell line

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.01 % Thiomersal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur Retinoblastoma 1

Antigène: Retinoblastoma 1 (RB1)

Autre désignation: Rb1

ID gène: 5925, 19645

OMIM: 614041

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy