Kallikrein 7 anticorps (N-Term)

N° du produit ABIN488082

Détail du produit anti-Kallikrein 7 anticorps

Antigène: Kallikrein 7 (KLK7)

Épitope: AA 1-237, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes Kallikrein-7/KLK7.
Cellular Localization: Secreted.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 237 of Human KLK7

Information d'application

Indications d'application: Western blotting: 1/500-1/3000. Positive Controls: 293TImmunohistochemistry on Formalin-Fixed Paraffin-Embedded Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted at (in aliquots) at -20 °C.

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: KLK7 / Kallikrein-7 (KLK7 Produits)

Synonymes: anticorps Prss6, anticorps SCCE, anticorps PRSS6, anticorps hK7, anticorps kallikrein related-peptidase 7 (chymotryptic, stratum corneum), anticorps kallikrein-related peptidase 7, anticorps kallikrein related peptidase 7, anticorps Klk7, anticorps KLK7

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.Synonyms: PRSS6, SCCE, Serine protease 6, Stratum corneum chymotryptic enzyme, hK7

ID gène: 5650, 9606

UniProt: P49862

Pathways: Système du Complément