RAMP2 anticorps (AA 111-175)

N° du produit ABIN488105

L’anticorps anti-RAMP2 Polyclonal Lapin est utilisé pour la détection de RAMP2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour RAMP2 anticorps (AA 111-175) (ABIN488105)

Antigène: RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAMP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAMP2 anticorps

Épitope: AA 111-175

Specificité: Recognizes RAMP2
Cellular Localization: Membrane, Single-pass type I membrane protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 111 and 175 of Human RAMP2

Information d'application

Indications d'application: Western blot: 1/500-1/3000Positive Controls: Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted at (in aliquots) at -20 °C.

Détails sur RAMP2

Antigène: RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))

Autre désignation: RAMP2

Sujet: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called Receptor (calcitonin) Activity Modifying Proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport Calcitonin-Receptor-like Receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.Synonyms: CRLR activity-modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, Receptor activity-modifying protein 2

Poids moléculaire: 20 kDa

ID gène: 10266, 9606

UniProt: O60895

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling