CD34 anticorps (Biotin)

N° du produit ABIN488155

Cet anticorps Souris Monoclonal détecte spécifiquement CD34 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD34 anticorps (Biotin) (ABIN488155)

Antigène: CD34

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: 4H11

Détail du produit anti-CD34 anticorps (Biotin)

Specificité: This antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.

Réactivité croisée (Details): Species reactivity (tested):Human

Attributs du produit: Synonyms: Hematopoietic progenitor cell marker, Hematopoietic progenitor cell antigen CD34

Immunogène: Permanent human cell line derived from peripheral leucocytes of a patient suffering fromchronic myeloid leukaemia

Isotype: IgG1

Information d'application

Indications d'application: Indirect immunofluorescence analysis by Flow cytometry (1: 200 as starting point.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker

ID gène: 947

UniProt: P28906