APC2 anticorps (N-Term)

N° du produit ABIN4886464

Cet anticorps Lapin Polyclonal détecte spécifiquement APC2 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour APC2 anticorps (N-Term) (ABIN4886464)

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-APC2 anticorps

Épitope: N-Term

Fonction: Anti-APC2 Antibody

Séquence: KHLQGKLEQE ARVLVSSGQT EVLEQLKALQ MDITSLYNLK

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by two amino acids.

Attributs du produit: Anti-APC2 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur APC2

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Autre désignation: APC2

Sujet:

Background: APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

Gene Full Name: APC regulator of Wnt signaling pathway 2

Poids moléculaire: 94 kDa

ID gène: 10297

UniProt: O95996

Pathways: Signalisation WNT