APOA1 anticorps (AA 25-267)

N° du produit ABIN4886466

Détail du produit anti-APOA1 anticorps

Antigène: APOA1 (Apolipoprotein A-I (APOA1))

Épitope: AA 25-267

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: apolipoprotein A-I
Protein Name: Apolipoprotein A-I

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human APOA1 recombinant protein (Position: D25-Q267). Human APOA1 shares 64% and 61.7% amino acid (aa) sequence identity with mouse and rat APOA1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur APOA1

Antigène: APOA1 (Apolipoprotein A-I (APOA1))

Autre désignation: APOA1 (APOA1 Produits)

Synonymes: anticorps Alp-1, anticorps Apoa-1, anticorps Brp-14, anticorps Ltw-1, anticorps Lvtw-1, anticorps Sep-1, anticorps Sep-2, anticorps Sep2, anticorps apoA-I, anticorps apoa, anticorps apoa1, anticorps cb49, anticorps wu:fb33f01, anticorps zgc:103718, anticorps MGC64335, anticorps MGC89745, anticorps Apo-AI, anticorps ApoA-I, anticorps APOA1, anticorps LOC100136573, anticorps apoa-i, anticorps ApoAI, anticorps apolipoprotein A1, anticorps apolipoprotein A-I, anticorps apolipoprotein A-Ia, anticorps apolipoprotein A-I S homeolog, anticorps apolipoprotein A4, anticorps APOA1, anticorps Apoa1, anticorps apoa1a, anticorps apoa1.S, anticorps apoa1, anticorps LOC100136573, anticorps apoa-i, anticorps apoa4

Sujet: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

Synonyms: Apo AI | APOA 1 | ApoA I | APOA1 | ApoA-I | Apo-AI | Apolipoprotein A I | Apolipoprotein A1 | Apolipoprotein AI | Apolipoprotein A-I | Apolipoprotein A-I(1-242) | ProapoA-I | Proapolipoprotein A-I | Truncated apolipoprotein A-I | P02647

ID gène: 335

UniProt: P02647

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism