Caldesmon anticorps (AA 1-120)

N° du produit ABIN4886498

Détail du produit anti-Caldesmon anticorps

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Épitope: AA 1-120

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caldesmon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Caldesmon(CALD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Caldesmon(CALD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: caldesmon 1
Protein Name: Caldesmon

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Caldesmon recombinant protein (Position: M1-E120). Human Caldesmon shares 87.6% amino acid (aa) sequence identity with rat Caldesmon.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Caldesmon

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Autre désignation: CALD1 (CALD1 Produits)

Synonymes: anticorps CDM, anticorps H-CAD, anticorps HCAD, anticorps L-CAD, anticorps LCAD, anticorps NAG22, anticorps l-Cad, anticorps 4833423D12Rik, anticorps AI195384, anticorps AV071549, anticorps AW536160, anticorps C920027I18Rik, anticorps CALD1, anticorps Caldesmon, anticorps caldesmon 1, anticorps CALD1, anticorps Cald1

Sujet: Caldesmon is a protein that in humans is encoded by the CALD1 gene. It is mapped to 7q33. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Synonyms: CAD | CALD 1 | CALD1 | CALD-1 | Caldesmon 1 | Caldesmon1 | Caldesmon-1 | Caldesmon | CDM | HCAD | H CAD | H-CAD | LCAD | L CAD | L-CAD | NAG22 | Q05682

ID gène: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction