Cnpase anticorps (Middle Region)

N° du produit ABIN4886542

Cet anticorps Lapin Polyclonal détecte spécifiquement Cnpase dans WB. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour Cnpase anticorps (Middle Region) (ABIN4886542)

Antigène: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cnpase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cnpase anticorps

Épitope: AA 142-178, Middle Region

Fonction: Anti-CNPase Antibody Picoband®

Séquence: QYQVVLVEPK TAWRLDCAQL KEKNQWQLSA DDLKKLK

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CNPase Antibody Picoband® (ABIN4886542). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CNPase, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: CNP 2',3'-cyclic nucleotide 3' phosphodiesterase". 2. Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR (Jan 2008). "Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts". Glia. 56 (1): 118-33. 3. Sprinkle TJ, Lanclos KD, Lapp DF (Jul 1992). "Assignment of the human 2',3'-cyclic nucleotide 3'-phosphohydrolase gene to chromosome 17".Genomics. 13 (3): 877-80.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-Cnpase (ABIN4886542)

Cai, Ma, Li, Tian, Li: "Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway." dans: International journal of biological sciences, Vol. 12, Issue 12, pp. 1415-1426, (2017) (PubMed).

Détails sur Cnpase

Antigène: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Autre désignation: CNP

Sujet:

Synonyms: 2',3'-cyclic-nucleotide 3'-phosphodiesterase,CNP,CNPase,3.1.4.37,CNP,

Background: 2',3'-Cyclic-nucleotide 3'-phosphodiesterase, also known as CNPase, is an enzyme that in humans is encoded by the CNP gene. And this gene is mapped to 17q21.2. CNPase is named for its ability to catalyze the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. CNPase is thought to play a critical role in the events leading up to myelination. Additionally, CNPase has been demonstrated to inhibit the replication of HIV-1 and other primate lentiviruses by binding the retroviral Gag protein and inhibiting the genesis of nascent viral particles.

Poids moléculaire: 47 kDa

ID gène: 1267

UniProt: P09543