Fibrinogen beta Chain anticorps (Middle Region)

N° du produit ABIN4886579

L’anticorps Lapin Polyclonal anti-Fibrinogen beta Chain a été validé pour WB, ICC, FACS et IF. Il convient pour détecter Fibrinogen beta Chain dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Fibrinogen beta Chain anticorps (Middle Region) (ABIN4886579)

Antigène: Fibrinogen beta Chain (FGB)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrinogen beta Chain est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-Fibrinogen beta Chain anticorps

Épitope: AA 193-225, Middle Region

Fonction: Anti-Fibrinogen beta chain/FGB Antibody Picoband®

Séquence: TNLRVLRSIL ENLRSKIQKL ESDVSAQMEY CRT

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Fibrinogen beta chain/FGB Antibody Picoband® (ABIN4886579). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human FGB, different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: FGB fibrinogen beta chain". 2. Chung, D. W., Que, B. G., Rixon, M. W., Mace, M., Jr., Davie, E. W. Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen. Biochemistry 22: 3244-3250, 1983. 3. Spena, S., Duga, S., Asselta, R., Malcovati, M., Peyvandi, F., Tenchini, M. L. Congenital afibrinogenemia: first identification of splicing mutations in the fibrinogen B-beta-chain gene causing activation of cryptic splice sites. Blood 100: 4478-4484, 2002.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Fibrinogen beta Chain

Antigène: Fibrinogen beta Chain (FGB)

Autre désignation: FGB

Sujet:

Synonyms: Fibrinogen beta chain,Fibrinopeptide B,Fibrinogen beta chain,FGB,

Tissue Specificity: Detected in blood plasma (at protein level). .

Background: Fibrinogen beta chain, mapped to 4q31.3, is also known as FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 56 kDa

ID gène: 2244

UniProt: P02675