MUC3B anticorps (C-Term)

N° du produit ABIN4886675

L’anticorps anti-MUC3B Polyclonal Lapin est utilisé pour la détection de MUC3B dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MUC3B anticorps (C-Term) (ABIN4886675)

Antigène: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC3B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MUC3B anticorps

Épitope: C-Term

Fonction: Anti-MUC3/MUC3A/MUC3B Antibody

Séquence: DLNDNTSQAY RDFNKTFWNQ MQKIFADMQG FTFK

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-MUC3/MUC3A/MUC3B Antibody (ABIN4886675). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human MUC3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur MUC3B

Antigène: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Autre désignation: MUC3B

Sujet:

Synonyms: Mucin-3B ,MUC-3B ,Intestinal mucin-3B ,MUC3B ,

Tissue Specificity: Fetal and adult small intestine and fetal and adult colon. .

Background: MUC3 consists of two genes, MUC3A and MUC3B, each encoding membrane-bound mucins possessing 2 epidermal growth factor-like domains. The MUC3 gene is mapped to chromosome 7. It was showed that synthetic peptide-mediated upregulation of MUC3 dramatically inhibited adherence of enteropathogenic E. coli or enterohemorrhage E. coli serotype O157:H7 to HT-29 human intestinal epithelial cells. Peptide stimulation altered expression of a number of transcription factors, including upregulation of SP1, CREB1, and CDX2. These transcription factors bound to consensus sites in the MUC3 promoter upon peptide stimulation and likely mediated MUC3 upregulation.

Poids moléculaire: 345 kDa

ID gène: 4584, 57876

UniProt: Q9H195