SRI anticorps (Middle Region)

N° du produit ABIN4886730

Cet anticorps anti-SRI est un anticorps Lapin Polyclonal détectant SRI dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour SRI anticorps (Middle Region) (ABIN4886730)

Antigène: SRI (Sorcin (SRI))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRI est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SRI anticorps

Épitope: AA 89-116, Middle Region

Fonction: Anti-SR1/SRI Antibody Picoband®

Séquence: TMGFNEFKEL WAVLNGWRQH FISFDTDR

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-SR1/SRI Antibody (ABIN4886730). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human SR1, different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: SRI sorcin". 2. Meyers, M B, Pickel V M, Sheu S S, Sharma V K, Scotto K W, Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 26411-8. 3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 5927-32.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur SRI

Antigène: SRI (Sorcin (SRI))

Autre désignation: SRI

Sujet:

Synonyms: Sorcin,22 kDa protein,CP-22,CP22,V19,SRI,

Tissue Specificity: Detected in cardiac myocytes.

Background: Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

Poids moléculaire: 26 kDa

ID gène: 6717

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity