Synapsin II (SYN2) (AA 497-582) anticorps

Détails pour le produit réf. ABIN4886735, Fournisseur: Connectez-vous pour afficher
Antigène
  • synII
  • synIIa
  • synIIb
  • syn1
  • syn2
  • zgc:92311
  • MGC115109
  • SYN2
  • SYNII
  • SYNIIa
  • SYNIIb
  • 2900074L19Rik
  • AI836018
  • AI841723
  • synapsin II L homeolog
  • synapsin II
  • synapsin IIa
  • synapsin II S homeolog
  • synapsin-2
  • syn2.L
  • SYN2
  • syn2a
  • syn2.S
  • EDI_190690
  • Syn2
Épitope
AA 497-582
2
2
2
2
2
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
33
32
31
1
Hôte
Lapin
37
2
2
Clonalité
Polyclonal
Conjugué
Inconjugué
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
28
13
12
10
4
3
3
1
1
Options
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N° du produit (Fournisseur)
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Fonction Rabbit IgG polyclonal antibody for Synapsin-2(SYN2) detection. Tested with WB in Human,Mouse,Rat.
Immunogène E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.
Isotype IgG
Réactivité croisée (Details) No cross reactivity with other proteins.
Attributs du produit Rabbit IgG polyclonal antibody for Synapsin-2(SYN2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: synapsin II
Protein Name: Synapsin-2
Purification Immunogen affinity purified.
Antigène
Autre désignation SYN2 (SYN2 Antibody Extrait)
Sujet Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.

Synonyms: SYN 2 | SYN II | SYN IIa | SYN IIb | SYN2 | Synapsin 2 | Synapsin2 | SynapsinII | SYNII | SYNIIa | SYNIIb | Q92777
ID gène 6854
UniProt Q92777
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Images (Fournisseur)
Western Blotting (WB) image for anti-Synapsin II (SYN2) (AA 497-582) antibody (ABIN4886735) Western blot analysis of Synapsin II expression in rat brain extract ( Lane 1), mouse...
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