SYN2 anticorps (AA 370-450)
Aperçu rapide pour SYN2 anticorps (AA 370-450) (ABIN7231614)
Antigène
Voir toutes SYN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 370-450
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Fonction
- Rabbit Anti-SYN2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SYN2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human SYN2 protein at AA range: 370-450
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- SYN2 (Synapsin II (SYN2))
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Autre désignation
- SYN2
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Sujet
- Synapsin-2, Synapsin IISYN2 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in SYN2 are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of SYN2 results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of SYN2 and is transcribed in the opposite direction.
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Poids moléculaire
- 64kD
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ID gène
- 6854
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UniProt
- Q92777
Antigène
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