KEAP1 anticorps (C-Term)

N° du produit ABIN4889301

Cet anticorps anti-KEAP1 est un anticorps Lapin Polyclonal détectant KEAP1 dans WB, ELISA, IF et ICC. Adapté pour Humain, Porc et Cobaye.

Aperçu rapide pour KEAP1 anticorps (C-Term) (ABIN4889301)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Humain, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KEAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-KEAP1 anticorps

Épitope: C-Term

Specificité: Reacts with KEAP1 from human, pig, guinea pig, sheep and other species (due to 100 % sequence homology)

Purification: Purified (protein A)

Immunogène: Synthetic peptide of derived from C terminal part of human KEAP1.

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:200) ICC/ IF(1:200 - 1:1000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: KEAP1

Sujet: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

ID gène: 9817

UniProt: Q14145

Pathways: Maintenance of Protein Location