Annexin a1 anticorps (AA 130-180)

N° du produit ABIN4900980

Cet anticorps anti-Annexin a1 est un anticorps Lapin Polyclonal détectant Annexin a1 dans WB, ELISA et IHC (p). Adapté pour Humain.

Aperçu rapide pour Annexin a1 anticorps (AA 130-180) (ABIN4900980)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Annexin a1 anticorps

Épitope: AA 130-180

Fonction: Annexin I is a protein encoded by the ANXA1 gene which is approximately 38,7 kDa. Annexin I is localised to the cell membrane. It is involved in peptide ligand-binding receptors, signalling by GPCR, cytokine signalling in immune system and RET signalling. It is a membrane-localized protein that binds phospholipids and plays an important role in the innate immune response as an effector of glucocorticoid-mediated responses and is a regulator of the inflammatory process. Annexin I is expressed in resting neutrophils. Mutations in the ANXA1 gene may result in hairy cell leukemia. STJ98699 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Annexin I.

Specificité: The antibody detects endogenous Annexin I.

Attributs du produit: Rabbit Polyclonal to Annexin I.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthetic peptide from human Annexin I protein.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000
IHC-P 1:50-300
ELISA 1:5000-20000

Commentaires:

Detected in resting neutrophils . Detected in peripheral blood T-cells . Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors . Detected in placenta (at protein level) . Detected in liver.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: Annexin I

Poids moléculaire: 38kDa

ID gène: 301

UniProt: P04083

Pathways: Hormone Transport